Monobenzone CAS 103-16-2

Monobenzone CAS 103-16-2 occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of monobenzone in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
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Product Details

Name: Monobenzone 

Other name:



Hydroquinone monobenzyl ether 


CAS: 103-16-2

EINECS: 203-083-3

MF: C13H12O2               

MW: 200.24

Appearance: White powder

MP: 117-122

Purity: 99%

Package: 1kg, 5kg, 25kg

Applications: Organic intermediate

  Monobenzone CAS 103-16-2 is a monobenzyl ether of hydroquinone with topical depigmentation activity. Although the exact mechanism of action of depigmentation is unknown, the metabolites of monobenzone appear to have a cytotoxic effect on melanocytes. Furthermore, the depigmentation effect might be mediated through the inhibition of tyrosinase, which is essential in the synthesis of melanin pigments, thereby causing permanent depigmentation of the skin.

Monobenzone CAS 103-16-2 is the monobenzyl ether of hydroquinone. It is used as a topical drug for medical depigmentation. It has a role as a melanin synthesis inhibitor and a dermatologic drug. It derives from a hydroquinone.

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