High Quality 99% API Fursultiamine powder CAS 804-30-8
Bevitol Lipophil ;
White crystalline powder
Fursultiamine CAS 804-30-8 is a nutritional supplement and vitamin B1 derivative, with potential antineoplastic activity. Upon oral administration, fursultiamine inhibits the expressions of octamer-binding transcription factor 4 (OCT-4), SRY (sex determining region Y)-box 2 (SOX-2), and Nanog homeobox (NANOG) in cancer stem cells (CSCs). This may inhibit the proliferation of CSCs thereby preventing tumor cell growth. In addition, fursultiamine inhibits the expression of ATP-binding cassette (ABC) transporters subfamily B member 1 (ABCB1) and subfamily G member 2 (ABCG2) in cancer CSCs, which may abrogate resistance to chemo- and radiotherapy in CSCs. CSCs promote tumor initiation, progression and metastasis; they play a key role in cancer recurrence and resistance to chemotherapy and radiation.
Fursultiamine CAS 804-30-8 has a molecular formula of C17H26N4O3S2 and a molecular weight of 398.55. Fursultiamine is a compound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful.
Fursultiamine CAS 804-30-8 could be supplied in commercial size with competitive price.