Pyrimidine-2-carbonitrile 2-Cyanopyrimidine CAS 14080-23-0 98% with high quality
Used as Cathepsin K inhibitor for the treatment of osteoperosis
Pyrimidine-2-carbonitrile CAS:14080-23-0 is a protease defined by its high specificity for kinins, which is involved in bone resorption. Cathepsin K's ability to catabolize collagen, elastin, and gelatin allow it to break down bone and cartilage. Such catabolic activity is also partially responsible for the loss of lung elasticity and recoil in emphysema. Therefore, inhibitors of Cathepsin K are showing great potential in the treatment of osteoporosis.