Chiral C2-symmetric vicinal diamines have emerged as powerful tools for the synthesis of enantiomerically pure compounds and are now commonly used as chiral auxiliaries or ligands for a wide array of asymmetric chemical transformations, with efficiencies comparable to those obtained with the closely related 1,2-diols. (1S,2S)- 1,2-Diaminocyclohexane (also named (IS,2S)-1,2-cyclohexanediamine), together with its (IR, 2R) enantiomer, allows excellent levels of asymmetric induction in many reactions, for which it has become the ligand of choice. Its applications in asymmetric synthesis and catalysis often involves the preparation of various AW-substituted derivatives.
(1R,2R)-(-)-1,2-Diaminocyclohexane CAS: 20439-47-8 is usually used as chiral auxiliary in many kinds of asymmetric organic reactions, which is made by resolution of 1,2-diaminocyclohexane.
(1R,2R)-(-)-1,2-Diaminocyclohexane CAS: 20439-47-8 is always available from Shanghai UCHEM Inc., together with its enantiomer ((1S)-(+)-trans-1,2-Diaminocyclohexane CAS: 21436-03-3) and other N-substituted derivatives. It is an off-white powder or pale-yellow oil, depending on the temperature, which could be dissolved in most of polar organic solvent.