Apremilast CAS:608141-41-9

Apremilast CAS:608141-41-9 is an orally available, small molecule inhibitor of phosphodiesterase-4 (PDE-4) and an immunomodulating agent that is used for treatment of refractory psoriatic arthritis. Apremilast has been linked to a low rate of serum enzyme elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury. Apremilast CAS:608141-41-9 is a member of the class of isoindoles that is isoindole-1,3-dione substituted at position 4 by an acetamido group and at position 1 by a 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl group. Used for treatment of psoriatic arthritis. It has a role as a phosphodiesterase IV inhibitor and a non-steroidal anti-inflammatory drug. It is an aromatic ether, a N-acetylarylamine, a sulfone and a member of phthalimides. Apremilast CAS:608141-41-9, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as [Roflumilast] and [Crisaborole]. Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and central nervous system inflammation.
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Product Details

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Product Description

Name

High quality API 98% ApreMilast CAS 608141-41-9 in stock

Other name

(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;

(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;

Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- ;

N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide

CAS

608141-41-9

Applications

API

Appearance

White powder

 

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Application

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Company Information

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Packaging & Shipping

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FAQ

Q1: Can I get some samples?
A: Yes, It is no problem.If you need sample ,please contact with us.
Q2: How to confirm the Product Quality before placing orders?
A:Firstly,we will send the sample for your testing and also provide our testing result.
Secondly,we could accept the third-party inspection.
Q3:What's your MOQ?
A:Normally,our MOQ is 1kg. But it could be according to your actual demandAny quantity is OK.
Q4: How about delivery time?
A:within 3-5 days after payment confirmed. (Chinese holiday not included)
Q5:Is there a discount?
A:Different quantity has different discount.
Q6: How do you treat quality complaint?
A:First of all, our quality control will ensure our quality in advance. If there is a real quality problem caused by us, we will provide good product again or refund your loss.--2_15.png


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