1,1'-Bi-2-naphthol CAS:602-09-5

1,1'-Bi-2-naphthol CAS:602-09-5 is also named as BINOL. It used as a reagent in the synthesis of (rac)-1,1'-binaphthyl-based simple receptors which are designed for fluorometric discrimination of maleic and fumaric acids. It is also used as a reagent in the synthesis of Dinaphtho[2,1-b:1',2'-d]furan; a compound which can induce aryl hydrocarbon receptor-mediated and estrogen receptor-mediated activities and can also modulate cell proliferation. 1,1'-Bi-2-naphthol CAS:602-09-5 is an organic compound that is often used as a ligand for transition-metal catalysed asymmetric synthesis. BINOL has axial chirality and the two enantiomers can be readily separated and are stable toward racemisation. 1,1'-Bi-2-naphthol CAS:602-09-5 could be supplied in different size with competitive price.
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Product Details

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Product Description

Name

High Prity BINOL 99% 1,1'-Bi-2-naphthol CAS 602-09-5

Other name

[1,1'-binaphthalene]-2,2'-diol; 1,1'-bi-2-naphthol; 1,1-binaphthol; BINOL

CAS

602-09-5

Appearance

white powder

Purity

99%min.

Applications

Raw material for chiral BINOL or BINAP.

BINOL CAS:602-09-5 could be converted to optical pure R-BINOL or S-BINOL through resolution. Currently, producing larger quantity of both enantiomers through resolution is more economic and effective way. Previously reported resolutions include: 1) making a cyclic phosphate of binaphthol, then resolution and subsequent reduction to release the pure binaphthol;  2) using enzymatic hydrolysis of the diester of binaphthol; and  3) forming inclusion complexes with suitable compounds. The use of N-benzylcinchonidinium chlorideto make inclusion complexes was reported by Tanaka and co-workers for obtaining one enantiomer of binaphthol.Using acetonitrileas solvent, in which the inclusion complex has very low solubility, allows for the isolation of both enantiomers with high enantiomeric excess. This simple and efficient procedure represents a much better resolution for 1,1'-bi-2-naphthol.

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Application

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FAQ

Q1: Can I get some samples?
A: Yes, It is no problem.If you need sample ,please contact with us.
Q2: How to confirm the Product Quality before placing orders?
A:Firstly,we will send the sample for your testing and also provide our testing result.
Secondly,we could accept the third-party inspection.
Q3:What's your MOQ?
A:Normally,our MOQ is 1kg. But it could be according to your actual demandAny quantity is OK.
Q4: How about delivery time?
A:within 3-5 days after payment confirmed. (Chinese holiday not included)
Q5:Is there a discount?
A:Different quantity has different discount.
Q6: How do you treat quality complaint?
A:First of all, our quality control will ensure our quality in advance. If there is a real quality problem caused by us, we will provide good product again or refund your loss.--2_15.png


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